Sensitive Superoxide Detection in Vascular Cells by the New Chemiluminescence Dye L-012
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چکیده
منابع مشابه
Sensitive superoxide detection in vascular cells by the new chemiluminescence dye L-012.
The detection superoxide production in vascular cells is usually limited by a low sensitivity of available assays. We tested the applicability of the luminol derivate L-012 ¿8-amino-5-chloro-7-phenylpyridol¿3,4-dpyridazine-1,4(2H,3H)dione to measure superoxide production in cultured endothelial cells (human umbilical vein endothelial cells) and rat aortic segments. Following stimulation with t...
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During the past decade, it has become apparent that reactive oxygen species play a critical role in the genesis of many vascular diseases. The superoxide anion is among the most important of these, not only because of its rapid reaction with NO but also because it serves as a progenitor for many other reactive oxygen species. Although there are many approaches to detecting and quantifying super...
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ژورنال
عنوان ژورنال: Journal of Vascular Research
سال: 1999
ISSN: 1018-1172,1423-0135
DOI: 10.1159/000025688